Gene Expression Patterns in Visceral and Subcutaneous Adipose Depots in Rats are Linked to Their Morphologic Features
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چکیده
منابع مشابه
Humans and Mice Display Opposing Patterns of “Browning” Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots
Visceral adiposity is much more strongly associated with cardiometabolic disease in humans than subcutaneous adiposity. Browning, the appearance of brown-like adipocytes in the white adipose tissue (WAT), has been shown to protect mice against metabolic dysfunction, suggesting the possibility of new therapeutic approaches to treat obesity and type 2 diabetes. In mice, subcutaneous WAT depots ex...
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Background and Objectives: The P53 is one of the genes involved in weight management. This study investigated associations of dietary intakes, anthropometric measurements and insulin resistance with relative P53 gene expressions. Materials & Methods: Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were collected from 151 individuals, aging nearly 40 years, who underwent el...
متن کاملDifferential response to caloric restriction of retroperitoneal, epididymal, and subcutaneous adipose tissue depots in rats
The beneficial actions of caloric restriction (CR) are partially mediated by metabolic remodeling of white adipose tissue (WAT). Recently, we showed that CR enhances de novo fatty acid (FA) biosynthesis and mitochondrial biogenesis, particularly in WAT. Here, to better understand the response of WAT to CR, we compare the effects of CR on three WAT depots in rats: retroperitoneal (rWAT), epididy...
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Introduction: Omentin, an adipokine, with anti-inflammatory effects reduces insulin resistance, and can hence, play an important role in prevention of cardiovascular disease and diabetes. The present study aimed to investigate the association of plasma and dietary fatty acids with gene expression of omentin in visceral and subcutaneous adipose tissues. Materials and Methods: Visceral and subcut...
متن کاملDifferential responses of visceral and subcutaneous fat depots to nutrients.
Increased visceral adiposity is a pivotal component of the metabolic syndrome. Differential gene expression patterns of fat-derived peptides (FDPs) in visceral fat and subcutaneous fat have been characterized in the fasting state. Here we examined whether delivery of nutrients differentially affects the expression of FDPs in visceral fat versus subcutaneous fat (in the fed state). We increased ...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2009
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000257511